GNA15 anticorps

N° du produit ABIN488048

Détail du produit anti-GNA15 anticorps

Antigène: GNA15 (Guanine Nucleotide Binding Protein (G Protein), alpha 15 (Gq Class) (GNA15))

Reactivité: Humain, Souris, Rat, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GNA15 est non-conjugé

Application: Western Blotting (WB)

Specificité: The antibody detects GA15 in samples from Human, Mouse, Rat, and Rabbit origins. It also detects GA16 from samples of Human origin.

Purification: Affinity Chromatography.

Immunogène: Synthetic peptide surrounding amino acid 356 of Human G Protein Alpha 15

Information d'application

Indications d'application: Western blotting (0.5-4 μg/mL). From Researcher's feedback, the antibody can be used in Immunohistochemistry (5-20 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS ( pH 7.2) containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal as preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Détails sur GNA15

Antigène: GNA15 (Guanine Nucleotide Binding Protein (G Protein), alpha 15 (Gq Class) (GNA15))

Autre désignation: G Protein alpha 15 (GNA15 Produits)

Synonymes: anticorps GNA16, anticorps G[a]15, anticorps Galpha15, anticorps G protein subunit alpha 15, anticorps guanine nucleotide binding protein (G protein), alpha 15 (Gq class), anticorps guanine nucleotide binding protein, alpha 15, anticorps GNA15, anticorps Gna15

Sujet: G Protein alpha 16 (GA16) is the only heterotrimeric G protein with a restricted expression pattern in hematopoietic cells. Differentiation of promyelocytic cells leads to decreased expression of GA16. The G protein is known to couple a large number of G protein-coupled receptors to PLC-beta and can lead to production of the secondary messengers diacylglycerol and inositol phosphates. Targeted deletion of GA15, a mouse orthologue of human GA16, causes reduced C5α receptor signaling. GA16 serves as a marker, in addition to CD34, for hematopoietic progenitor cells.Synonyms: G alpha-15, GNA15, GNA16, Guanine nucleotide-binding protein subunit alpha-15

ID gène: 2769

NCBI Accession: NP_002059

UniProt: P30679