EPH Receptor A2 anticorps

N° du produit ABIN488132

L’anticorps Souris Monoclonal anti-EPH Receptor A2 a été validé pour FACS, IF et EIA. Il convient pour détecter EPH Receptor A2 dans des échantillons de Humain.

Aperçu rapide pour EPH Receptor A2 anticorps (ABIN488132)

Antigène: EPH Receptor A2 (EPHA2)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EPH Receptor A2 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Clone: GM5H5

Détail du produit anti-EPH Receptor A2 anticorps

Specificité: Recognizes EphA2 receptor tyrosine kinase (EphA2).

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography on Protein G.

Immunogène: Genetic immunisation with cDNA encoding Human EphA2 Remarks: Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells

Isotype: IgG1

Information d'application

Indications d'application: cELISA: 1/200-1/400. Flow Cytometry: 1.2 μg/10^6 cells. Immunofluorescence: 1 μg/10^6 cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 2.0 mg/mL

Buffer: Phosphate buffered saline, pH 7.2

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur EPH Receptor A2

Antigène: EPH Receptor A2 (EPHA2)

Autre désignation: EPHA2 / ECK

Sujet: EphA2 (Eph receptor tyrosine kinase A2) belongs to the Eph tyrosine receptor familiy, the largest receptor tyrosine kinase family of transmembrane proteins. It encodes a 130 kDA transmembrane protein which is primarily found in adult human epithelial cells (1). Eph receptors and their ephrin ligands are important mediators of cell-cell communication and play roles in embryonic patterning, neuronal targeting, and vascular development during normal embryogenesis (2,3). The Eph family of receptor tyrosine kinases is frequently overexpressed in a wide variety of cancers and tumor cell lines. In particular, EphA2 is overexpressed in prostate, lung and colon cancers and 40 % of breast cancers and it represent an attractive potential target for drug design (3,4).Synonyms: Eph receptor A2, Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK

ID gène: 1969

NCBI Accession: NP_004422

UniProt: P29317

Pathways: Signalisation RTK