CD11b anticorps (AA 260-360)
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- Antigène Voir toutes CD11b (ITGAM) Anticorps
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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Épitope
- AA 260-360
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CD11b est non-conjugé
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Application
- Western Blotting (WB)
- Fonction
- Rabbit IgG polyclonal antibody for Integrin alpha-M(ITGAM) detection. Tested with WB in mouse.
- Réactivité croisée (Details)
- No cross reactivity with other proteins.
- Attributs du produit
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Rabbit IgG polyclonal antibody for Integrin alpha-M(ITGAM) detection. Tested with WB in mouse.
Gene Name: integrin alpha M
Protein Name: Integrin alpha-M - Purification
- Immunogen affinity purified.
- Immunogène
- E. coli-derived mouse CD11b recombinant protein (Position: E260-T360). Mouse CD11b shares 82.2% amino acid (aa) sequence identity with human CD11b.
- Isotype
- IgG
- Top Product
- Discover our top product ITGAM Anticorps primaire
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- Indications d'application
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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Expressions of CD11a, CD11b, and CD11c integrin proteins in rats with myocardial hypertrophy." dans: Iranian journal of basic medical sciences, Vol. 17, Issue 11, pp. 874-8, (2015) (PubMed).
: "Ethyl pyruvate promotes spinal cord repair by ameliorating the glial microenvironment." dans: British journal of pharmacology, Vol. 166, Issue 2, pp. 749-63, (2012) (PubMed).
: "Anti-heat shock protein 70 autoantibody epitope changes and BD091 promotes atherosclerosis in rats." dans: Cell stress & chaperones, Vol. 15, Issue 6, pp. 947-58, (2011) (PubMed).
: "Cloning, characterization, and expression analysis of goat (Capra hircus) phospholipid hydroperoxide glutathione peroxidase (PHGPx)." dans: International journal of biological sciences, Vol. 6, Issue 4, pp. 316-26, (2010) (PubMed).
: "
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Expressions of CD11a, CD11b, and CD11c integrin proteins in rats with myocardial hypertrophy." dans: Iranian journal of basic medical sciences, Vol. 17, Issue 11, pp. 874-8, (2015) (PubMed).
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- Antigène
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- Autre désignation
- ITGAM (ITGAM Produits)
- Synonymes
- anticorps CD11b/CD18, anticorps CR3, anticorps CR3A, anticorps Cd11b, anticorps F730045J24Rik, anticorps Ly-40, anticorps MAC1, anticorps Mac-1, anticorps Mac-1a, anticorps CD11B, anticorps MAC-1, anticorps MAC1A, anticorps MO1A, anticorps SLEB6, anticorps C3bi, anticorps integrin subunit alpha M, anticorps integrin alpha M, anticorps integrin, alpha M (complement component 3 receptor 3 subunit), anticorps integrin alpha-M, anticorps ITGAM, anticorps Itgam, anticorps LOC100351865
- Sujet
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Integrin alpha M (ITGAM) is one protein subunit that forms the heterodimeric integrin alpha-M beta-2 (αMβ2) molecule, also known as macrophage-1 antigen (Mac-1) or cluster of differentiation molecule 11B (CD11B). It is mapped to 16p11.2. ITGAM has a role in vascular repair after mechanical arterial injury. It is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. What's more, ITGAM probably recognizes the R-G-D peptide in C3b, and it is also a receptor for fibrinogen, factor X and ICAM1.
Synonyms: CD11b antigen | CD11B | CR3A | Integrin alpha-M | ITAM | ITGAM | Leukocyte adhesion receptor MO1 | mac-1 | Mac1, alpha subunit | Mo1, alpha subunit | SLEB6 | P11215 - ID gène
- 16409
- UniProt
- P05555
- Pathways
- Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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