PNP anticorps (Middle Region)

N° du produit ABIN4886701

Détail du produit anti-PNP anticorps

Antigène: PNP (NP) (Nucleoside Phosphorylase (NP))

Épitope: AA 161-189, Middle Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PNP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Purine nucleoside phosphorylase(PNP) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: AMSDAYDRTM RQRALSTWKQ MGEQRELQE

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Purine nucleoside phosphorylase(PNP) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: purine nucleoside phosphorylase
Protein Name: Purine nucleoside phosphorylase

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human PNP (161-189aa AMSDAYDRTMRQRALSTWKQMGEQRELQE), different from the related mouse sequence by six amino acids, and from the related rat sequence by five amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur PNP

Antigène: PNP (NP) (Nucleoside Phosphorylase (NP))

Autre désignation: PNP (NP Produits)

Synonymes: anticorps NP, anticorps PRO1837, anticorps PUNP, anticorps Np, anticorps AL024301, anticorps AU015798, anticorps Np-1, anticorps Np-2, anticorps Pnp1, anticorps purine nucleoside phosphorylase, anticorps purine-nucleoside phosphorylase, anticorps PNP, anticorps Pnp

Classe de substances: Viral Protein

Sujet: The PNP gene encodes purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised T-lymphocyte function and neurologic dysfunction.

Synonyms: Inosine phosphorylase | NP | Np1 | Nucleoside phosphorylase | PNP | Pnp1 | PRO1837 | PUNP | P00491

ID gène: 4860

UniProt: P00491

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus