TACI anticorps
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- Antigène Voir toutes TACI (TNFRSF13B) Anticorps
- TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))
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Reactivité
- Humain
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Hôte
- Rat
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp TACI est non-conjugé
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Application
- Flow Cytometry (FACS)
- Specificité
- The rat monoclonal antibody 1A1 recognizes an extracellular epitope of CD267 / TACI, a 32 kDa type III transmembrane protein expressed by B cells and possibly by some activated T cells.
- Réactivité croisée (Details)
- Human
- Purification
- Purified by protein-G affinity chromatography.
- Pureté
- > 95 % (by SDS-PAGE)
- Immunogène
- CD267-transfected RBL cells
- Clone
- 1A1
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product TNFRSF13B Anticorps primaire
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- Indications d'application
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Do not freeze.
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- Antigène
- TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))
- Autre désignation
- CD267 / TACI (TNFRSF13B Produits)
- Synonymes
- anticorps CD267, anticorps CVID, anticorps CVID2, anticorps RYZN, anticorps TACI, anticorps TNFRSF14B, anticorps TNFRSF13B, anticorps 1200009E08Rik, anticorps Taci, anticorps TNF receptor superfamily member 13B, anticorps tumor necrosis factor receptor superfamily, member 13b, anticorps TNFRSF13B, anticorps Tnfrsf13b
- Sujet
- TNF receptor superfamily member 13B,CD267 / TACI (transmembrane activator calcium modulator and cyclophilin ligand interactor), a TNFR superfamily transmembrane protein, is expressed on B cells (predominantly on CD27+ memory cells), multiple myeloma cells and B cell chronic lymphocytic leukemia (B-CLL). Its triggering leads to activation of the transcription factors NFAT, AP1, and NF-kappa-B. It plays a crucial role in humoral immunity. Mutations in CD267 are associated with common variable immunodeficiency and IgA deficiency.,RYZN, TACI, CVID2, IGAD2, TNFRSF14B
- ID gène
- 23495
- UniProt
- O14836
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