FGFR2 anticorps (AA 809-821)

N° du produit ABIN490845

Cet anticorps anti-FGFR2 est un anticorps Lapin Polyclonal détectant FGFR2 dans WB, IHC, IHC (p) et IP. Adapté pour Humain.

Aperçu rapide pour FGFR2 anticorps (AA 809-821) (ABIN490845)

Antigène: FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGFR2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Détail du produit anti-FGFR2 anticorps

Épitope: AA 809-821

Specificité: FGFR2, Cytoplasmic reacts specifically with FGFR2 using immunoblotting and immunoprecipitation (doublet at 115-125kD) using whole cell lysates of transfected 293T cells, a human, embryonic kidney cell line, expressing recombinant human FGFR2. No reaction with human FGFR1 and FGFR3 is detected. Species cross-reactivity: Human. Expected to cross-react with Mouse (92 % identity with immunogen) and Rat (92 % identity with immunogen) due to sequence homology.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Mouse, Rat, Hamster, Elephant, Horse (92%) Panda, Bovine, Dog (85%).

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide: KLPQYPHIGSVKT conjugated to KLH by a Glutaraldehyde linker, corresponding to amino acids 809-821 of the cytoplasmic region of Human FGFR2. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Mouse, Rat, Hamster, Elephant, Horse (92%), Panda, Bovine, Dog (85%).

Type of Immunogen: Synthetic peptide - KLH conjugated

Isotype: IgG

Information d'application

Indications d'application: Approved: IHC, IHC-P, IP (1:2000), WB (1:2000)

Usage: Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Immunohistochemistry (trypsin or protease-digested, formalin-fixed, paraffin-embedded tissue):1:250, Immunoprecipitation: 1:2000, Western Blot:1:2000. Positive control: 293T, embryonic kidney cell line.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 1 % BSA, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: avoid freeze thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Détails sur FGFR2

Antigène: FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

Autre désignation: FGF Receptor / FGFR2

Sujet: Name/Gene ID: FGFR2
Subfamily: FGF Receptor
Family: Protein Kinase

Synonyms: FGFR2, BEK, BBDS, Bacteria-expressed kinase, CD332 antigen, CFD1, Craniofacial dysostosis 1, CEK3, Fgf bek, FGF receptor, Hydroxyaryl-protein kinase, Jackson-Weiss syndrome, JWS, FGF Receptor 2, KSAM, KGFR, Soluble FGFR4 variant 4, BFR-1, TK14, TK25, CD332, ECT1, K-SAM

ID gène: 2263

UniProt: P21802

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding