NADPH Oxidase 4 anticorps

N° du produit ABIN4949834

Cet anticorps anti-NADPH Oxidase 4 est un anticorps Souris Monoclonal détectant NADPH Oxidase 4 dans WB, ELISA, FACS et IF. Adapté pour Humain.

Aperçu rapide pour NADPH Oxidase 4 anticorps (ABIN4949834)

Antigène: NADPH Oxidase 4 (NOX4)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NADPH Oxidase 4 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: NOX4-1245

Détail du produit anti-NADPH Oxidase 4 anticorps

Purification: Protein G affinity chromatography

Immunogène: Human recombinant protein was used as the immunogen for this NOX4 antibody.

Isotype: IgG2b kappa

Information d'application

Indications d'application: Titering of the NOX4 antibody may be required for optimal performance.\. FACS: 0.5-1 μg/10^6 cells in 0.1ml,IF: 1-2 μg/mL,ELISA: suitable, order BSA-free formulation for coating,WB: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the NOX4 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur NADPH Oxidase 4

Antigène: NADPH Oxidase 4 (NOX4)

Autre désignation: NOX4

Sujet: The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. NOX4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. It is also expressed in fetal tissues, placenta, glioblastoma and vascular cells.

ID gène: 4821

Pathways: Carbohydrate Homeostasis, Smooth Muscle Cell Migration