KAT2A anticorps

N° du produit ABIN4951155

Détail du produit anti-KAT2A anticorps

Antigène: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KAT2A est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: Amino acids DPARPGLSQQQRASQRKAQVRGLPRAKKLEKL of human KAT2A/GCN5 were used as the immunogen for the GCN5 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the GCN5 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the GCN5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur KAT2A

Antigène: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Autre désignation: GCN5 / KAT2A (KAT2A Produits)

Synonymes: anticorps KAT2A, anticorps GCN5L2, anticorps GCN5, anticorps PCAF-b, anticorps hGCN5, anticorps 1110051E14Rik, anticorps AW212720, anticorps Gcn5, anticorps Gcn5l2, anticorps mmGCN5, anticorps K(lysine) acetyltransferase 2A, anticorps lysine acetyltransferase 2A, anticorps histone acetyltransferase KAT2A, anticorps ras-related protein Rab-5C, anticorps KAT2A, anticorps LOC100176452, anticorps LOC100597293, anticorps Kat2a

Sujet: Histone acetyltransferase KAT2A, also called GCN5 and GCN5L2, is an enzyme that in humans is encoded by the KAT2A gene. It is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. The GCN5 protein, a regulator of transcription activation in yeast, promotes maximal levels of transcription by 2 transcriptional activators, GCN4 and the HAP2-HAP3-HAP4 complex. The GCN4 protein activates transcription of a large number of amino acid biosynthetic genes under limiting amino acid conditions and the HAP2-HAP3-HAP4 complex is thought to mediate transcription of genes involved in respiratory functions. GCN5 also functions as a repressor of NF-kappa-B by promoting ubiquitination of the NF-kappa-B subunit RELA in a HAT-independent manner.

UniProt: Q92830

Pathways: Chromatin Binding, Tube Formation