K(lysine) Acetyltransferase 2A (KAT2A) anticorps

Détails pour le produit réf. ABIN4951155
Antigène
  • KAT2A
  • GCN5L2
  • GCN5
  • PCAF-b
  • hGCN5
  • 1110051E14Rik
  • AW212720
  • Gcn5
  • Gcn5l2
  • mmGCN5
  • K(lysine) acetyltransferase 2A
  • lysine acetyltransferase 2A
  • histone acetyltransferase KAT2A
  • ras-related protein Rab-5C
  • KAT2A
  • LOC100176452
  • LOC100597293
  • Kat2a
Reactivité
Humain
82
27
10
3
Hôte
Lapin
64
19
Clonalité
Polyclonal
Conjugué
Inconjugué
2
2
2
2
2
2
Application
Western Blotting (WB)
77
43
14
7
7
5
4
3
1
Options
Immunogène Amino acids DPARPGLSQQQRASQRKAQVRGLPRAKKLEKL of human KAT2A/GCN5 were used as the immunogen for the GCN5 antibody.
Isotype IgG
Purification Antigen affinity
Antigène
Autre désignation GCN5 / KAT2A (KAT2A Antibody Extrait)
Sujet Histone acetyltransferase KAT2A, also called GCN5 and GCN5L2, is an enzyme that in humans is encoded by the KAT2A gene. It is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. The GCN5 protein, a regulator of transcription activation in yeast, promotes maximal levels of transcription by 2 transcriptional activators, GCN4 and the HAP2-HAP3-HAP4 complex. The GCN4 protein activates transcription of a large number of amino acid biosynthetic genes under limiting amino acid conditions and the HAP2-HAP3-HAP4 complex is thought to mediate transcription of genes involved in respiratory functions. GCN5 also functions as a repressor of NF-kappa-B by promoting ubiquitination of the NF-kappa-B subunit RELA in a HAT-independent manner.
UniProt Q92830
Pathways Chromatin Binding, Tube Formation
Indications d'application Optimal dilution of the GCN5 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL
Restrictions For Research Use only
Buffer 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock -20 °C
Stockage commentaire After reconstitution, the GCN5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Images (Fournisseur)
Image no. 1 for anti-K(lysine) Acetyltransferase 2A (KAT2A) antibody (ABIN4951155) Western blot testing of human 1) A431, 2) 22RV1 and 3) COLO320 lysate with GCN5 antib...
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