Angiotensin I Converting Enzyme 1 anticorps (AA 1274-1306)

N° du produit ABIN3029960

L’anticorps anti-Angiotensin I Converting Enzyme 1 Polyclonal Lapin est utilisé pour la détection de Angiotensin I Converting Enzyme 1 dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour Angiotensin I Converting Enzyme 1 anticorps (AA 1274-1306) (ABIN3029960)

Antigène: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiotensin I Converting Enzyme 1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Angiotensin I Converting Enzyme 1 anticorps

Épitope: AA 1274-1306

Fonction: ACE Antibody / Angiotensin-Converting Enzyme

Purification: Purified

Immunogène: A portion of amino acids 1274-1306 from the human protein was used as the immunogen for this ACE antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the ACE antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the ACE antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Angiotensin I Converting Enzyme 1

Antigène: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Autre désignation: ACE

Sujet: ACE is an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active.

UniProt: P12821

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration