TLR2 anticorps (AA 720-749)

N° du produit ABIN3029165

L’anticorps Lapin Polyclonal anti-TLR2 a été validé pour WB, IHC et ELISA. Il convient pour détecter TLR2 dans des échantillons de Humain et Souris.

Aperçu rapide pour TLR2 anticorps (AA 720-749) (ABIN3029165)

Antigène: TLR2 (Toll-Like Receptor 2 (TLR2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-TLR2 anticorps

Épitope: AA 720-749

Purification: Purified

Immunogène: A portion of amino acids 720-749 from the mouse protein was used as the immunogen for this anti-TLR2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the anti-TLR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the anti-TLR2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur TLR2

Antigène: TLR2 (Toll-Like Receptor 2 (TLR2))

Autre désignation: TLR2

Sujet: TLR2 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR2 is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

UniProt: Q9QUN7

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades