Bcl-2 anticorps (AA 86-114)

N° du produit ABIN3030099

Cet anticorps anti-Bcl-2 est un anticorps Lapin Polyclonal détectant Bcl-2 dans WB et ELISA. Adapté pour Humain et Souris.

Aperçu rapide pour Bcl-2 anticorps (AA 86-114) (ABIN3030099)

Antigène: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Bcl-2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Bcl-2 anticorps

Épitope: AA 86-114

Réactivité croisée (Details): Expected species reactivity: Bovine, Hamster, Rat

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 86-114 from the human protein was used as the immunogen for this BCL2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the BCL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the BCL2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur Bcl-2

Antigène: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Autre désignation: BCL2

Sujet: This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq].

UniProt: P10415

Pathways: Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling