IDH1 anticorps (AA 116-143)

N° du produit ABIN3031506

Cet anticorps anti-IDH1 est un anticorps Lapin Polyclonal détectant IDH1 dans WB, IHC, ELISA, FACS et IF. Adapté pour Humain et Souris.

Aperçu rapide pour IDH1 anticorps (AA 116-143) (ABIN3031506)

Antigène: IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IDH1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-IDH1 anticorps

Épitope: AA 116-143

Réactivité croisée (Details): Expected species reactivity: Rat, Bovine

Purification: Purified

Immunogène: A portion of amino acids 116-143 from the human protein was used as the immunogen for this IDH1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the IDH1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the IDH1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur IDH1

Antigène: IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))

Autre désignation: IDH1

Sujet: IDH1 belongs to two distinct subclasses. The protein is the NADP(+)-dependent Isocitrate Dehydrogenase found in the cytoplasm and peroxisomes. This protein contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. [Wiki]

UniProt: O75874

Pathways: L'effet Warburg