IGF1R anticorps (AA 19-51)
Aperçu rapide pour IGF1R anticorps (AA 19-51) (ABIN3031344)
Antigène
Voir toutes IGF1R AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 19-51
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Fonction
- IGF1R Antibody
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Réactivité croisée (Details)
- Expected species reactivity: Mouse, Rat
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Purification
- Purified
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Immunogène
- A portion of amino acids 19-51 from the human protein was used as the immunogen for this IGF1R antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the IGF1R antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the IGF1R antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
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Autre désignation
- IGF1R
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Sujet
- The IGF1 receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.
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UniProt
- P08069
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Pathways
- Signalisation RTK, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
Antigène
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