IRAK1 anticorps (AA 405-433)

N° du produit ABIN3028764

Cet anticorps anti-IRAK1 Polyclonal Lapin (ABIN3028764) détecte spécifiquement IRAK1 dans WB, ELISA et FACS. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour IRAK1 anticorps (AA 405-433) (ABIN3028764)

Antigène: IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRAK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-IRAK1 anticorps

Épitope: AA 405-433

Fonction: Irak1 Antibody

Purification: Antigen affinity

Immunogène: A portion of amino acids 405-433 from the mouse protein was used as the immunogen for this Irak1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Irak1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Irak1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur IRAK1

Antigène: IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

Autre désignation: Irak1

Sujet: Irak1 binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. The kinase activity of this enzyme may not be required for IL-1 signaling. Once phosphorylated, IRAK1 recruits the adapter protein PELI1.

UniProt: Q62406

Pathways: Signalisation NF-kappaB, Signalisation TLR, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades