IRAK4 anticorps (AA 25-52)

N° du produit ABIN3031497

Cet anticorps anti-IRAK4 Polyclonal Lapin (ABIN3031497) détecte spécifiquement IRAK4 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour IRAK4 anticorps (AA 25-52) (ABIN3031497)

Antigène: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRAK4 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-IRAK4 anticorps

Épitope: AA 25-52

Fonction: IRAK4 Antibody

Réactivité croisée (Details): Expected species reactivity: Mouse, Bovine

Purification: Antigen affinity

Immunogène: A portion of amino acids 25-52 from the human protein was used as the immunogen for this IRAK4 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the IRAK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot the IRAK4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur IRAK4

Antigène: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Autre désignation: IRAK4

Sujet: This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: Q9NWZ3

Pathways: Signalisation NF-kappaB, Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades