IRAK4 anticorps (AA 422-449)

N° du produit ABIN3028767

Cet anticorps anti-IRAK4 est un anticorps Lapin Polyclonal détectant IRAK4 dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour IRAK4 anticorps (AA 422-449) (ABIN3028767)

Antigène: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRAK4 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-IRAK4 anticorps

Épitope: AA 422-449

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 422-449 from the mouse protein was used as the immunogen for this Irak4 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Irak4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Irak4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur IRAK4

Antigène: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Autre désignation: Irak4

Sujet: Irak4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Phosphorylates IRAK1 (By similarity).

UniProt: Q8R4K2

Pathways: Signalisation NF-kappaB, Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades