IRAK4 anticorps (AA 422-449)
Aperçu rapide pour IRAK4 anticorps (AA 422-449) (ABIN3028767)
Antigène
Voir toutes IRAK4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 422-449
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Fonction
- Irak4 Antibody
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Purification
- Antigen affinity
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Immunogène
- A portion of amino acids 422-449 from the mouse protein was used as the immunogen for this Irak4 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the Irak4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Aliquot the Irak4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
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Autre désignation
- Irak4
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Sujet
- Irak4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Phosphorylates IRAK1 (By similarity).
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UniProt
- Q8R4K2
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Pathways
- Signalisation NF-kappaB, Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades
Antigène
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