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LCK anticorps (AA 23-52)

LCK Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, FACS Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3031644
  • Antigène Voir toutes LCK Anticorps
    LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))
    Épitope
    • 33
    • 18
    • 16
    • 11
    • 10
    • 8
    • 8
    • 7
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 23-52
    Reactivité
    • 177
    • 103
    • 65
    • 9
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 151
    • 24
    • 2
    Lapin
    Clonalité
    • 146
    • 32
    Polyclonal
    Conjugué
    • 100
    • 10
    • 10
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp LCK est non-conjugé
    Application
    • 132
    • 87
    • 32
    • 29
    • 24
    • 21
    • 16
    • 14
    • 13
    • 10
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
    Purification
    Antigen affinity purified
    Immunogène
    A portion of amino acids 23-52 from the human protein was used as the immunogen for this LCK antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product LCK Anticorps primaire
  • Indications d'application
    Titration of the LCK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot the LCK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Antigène
    LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))
    Autre désignation
    LCK (LCK Produits)
    Synonymes
    anticorps zgc:136695, anticorps LCK, anticorps Hck-3, anticorps Lsk, anticorps Lskt, anticorps p56, anticorps p56Lck, anticorps LSK, anticorps YT16, anticorps p56lck, anticorps pp58lck, anticorps P56LCK, anticorps tkl, anticorps Lck1, anticorps Lcktkr, anticorps LCK proto-oncogene, Src family tyrosine kinase, anticorps lymphocyte protein tyrosine kinase, anticorps lck, anticorps LCK, anticorps Lck
    Sujet
    LSK, which belongs to the SRC subfamily of Tyr protein kinases, may participate in antigen-induced T-cell activation. It binds to phosphatidylinositol 3'-kinase (PI3K) from T lymphocytes through its SH3 domain and to the tyrosine phosphorylated form of KHDRBS1/p70 through its SH2 domain. LSK is bound to the cytoplasmic domain of either CD4 or CD8. This protein is involved in leukemias by a chromosomal translocation t(1,7)(p34,q34) which involves LCK and T-cell receptor beta chain (TCRB) genes.
    UniProt
    P06239
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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