NLRP4 anticorps (AA 121-149)

N° du produit ABIN3032022

Cet anticorps anti-NLRP4 Polyclonal Lapin (ABIN3032022) détecte spécifiquement NLRP4 dans ELISA et WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour NLRP4 anticorps (AA 121-149) (ABIN3032022)

Antigène: NLRP4 (NLR Family, Pyrin Domain Containing 4 (NLRP4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP4 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-NLRP4 anticorps

Épitope: AA 121-149

Fonction: NLRP4 Antibody

Purification: Antigen affinity

Immunogène: A portion of amino acids 121-149 from the human protein was used as the immunogen for this NLRP4 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the NLRP4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot the NLRP4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur NLRP4

Antigène: NLRP4 (NLR Family, Pyrin Domain Containing 4 (NLRP4))

Autre désignation: NLRP4

Sujet: NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV, MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1, MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).

UniProt: Q96MN2

Pathways: Inflammasome