NLRP6 anticorps (AA 168-197)
Aperçu rapide pour NLRP6 anticorps (AA 168-197) (ABIN3032023)
Antigène
Voir toutes NLRP6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 168-197
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Fonction
- NLRP6 Antibody
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Purification
- Antigen affinity
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Immunogène
- A portion of amino acids 168-197 from the human protein was used as the immunogen for this NLRP6 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the NLRP6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the NLRP6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))
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Autre désignation
- NLRP6
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Sujet
- NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP6, have an N-terminal pyrin domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1, also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1) via their involvement in multiprotein complexes called inflammasomes.
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UniProt
- P59044
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Pathways
- Inflammasome
Antigène
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