NLRP6 anticorps (N-Term)

N° du produit ABIN657452

Détail du produit anti-NLRP6 anticorps

Antigène: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Épitope: AA 168-197, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP6 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This NLRP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-197 amino acids from the N-terminal region of human NLRP6.

Clone: RB33587

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. WB: 1:4000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: NLRP6 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur NLRP6

Antigène: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Autre désignation: NLRP6 (NLRP6 Produits)

Synonymes: anticorps NLRP6, anticorps NALP6, anticorps AVR, anticorps CLR11.4, anticorps NAVR, anticorps NAVR/AVR, anticorps PAN3, anticorps PYPAF5, anticorps AI504961, anticorps Avr, anticorps Nalp6, anticorps Navr, anticorps Navr/Avr, anticorps Pypaf5, anticorps NLR family pyrin domain containing 6, anticorps NLR family, pyrin domain containing 6, anticorps NLRP6, anticorps Nlrp6

Sujet: NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP6, have an N-terminal pyrin (MEFV, MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1, MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).

Poids moléculaire: 98768

ID gène: 171389

NCBI Accession: NP_001263629, NP_612202

UniProt: P59044

Pathways: Inflammasome