PAK2 anticorps (AA 192-222)

N° du produit ABIN3032117

L’anticorps Lapin Polyclonal anti-PAK2 a été validé pour WB, ELISA et IHC. Il convient pour détecter PAK2 dans des échantillons de Humain.

Aperçu rapide pour PAK2 anticorps (AA 192-222) (ABIN3032117)

Antigène: PAK2 (P21-Activated Kinase 2 (PAK2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAK2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-PAK2 anticorps

Épitope: AA 192-222

Purification: Purified

Immunogène: A portion of amino acids 192-222 from the human protein was used as the immunogen for this PAK2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the PAK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the PAK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur PAK2

Antigène: PAK2 (P21-Activated Kinase 2 (PAK2))

Autre désignation: PAK2

Sujet: PAK2, a member of the STE20 subfamily of Ser/Thr protein kinases, acts on a variety of targets. It phosphorylates ribosomal protein S6, histone H4 and myelin basic protein. PAK2 interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1. Expression is ubiquitous, with higher levels seen in skeletal muscle, ovary, thymus and spleen. PAK2 is autophosphorylated when activated by CDC42/p21. The protein structure contains 1 CRIB domain.

UniProt: Q13177

Pathways: Signalisation MAPK, Signalisation RTK, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha