PCSK7 anticorps (AA 692-721)

N° du produit ABIN3032338

Détail du produit anti-PCSK7 anticorps

Antigène: PCSK7 (Proprotein Convertase Subtilisin/kexin Type 7 (PCSK7))

Épitope: AA 692-721

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCSK7 est non-conjugé

Application: ELISA, Western Blotting (WB)

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 692-721 from the human protein was used as the immunogen for this PCSK7 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the PCSK7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the PCSK7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur PCSK7

Antigène: PCSK7 (Proprotein Convertase Subtilisin/kexin Type 7 (PCSK7))

Autre désignation: PCSK7 (PCSK7 Produits)

Synonymes: anticorps PC7, anticorps PCSK7, anticorps lpc, anticorps pc7, anticorps pc8, anticorps spc7, anticorps MGC115258, anticorps wu:fj05c03, anticorps zgc:158336, anticorps LPC, anticorps PC8, anticorps SPC7, anticorps AA959856, anticorps proprotein convertase subtilisin/kexin type 7, anticorps proprotein convertase subtilisin/kexin type 7 L homeolog, anticorps PCSK7, anticorps pcsk7.L, anticorps pcsk7, anticorps Pcsk7

Sujet: The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease. It is structurally related to its family members, PACE and PACE4. This protein is concentrated in the trans-Golgi network, associated with the membranes, and is not secreted. It can process proalbumin and is thought to be responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene has been implicated in the transcriptional regulation of housekeeping genes. Multiple alternatively spliced transcripts are described for this gene but their full length nature is not yet known. Downstream of this gene's map location at 11q23-q24, nucleotides that match part of this gene's 3' end are duplicated and inverted. A translocation breakpoint associated with lymphoma occurs between this gene and its inverted counterpart.

UniProt: Q16549