PDGFRA anticorps (AA 698-727)
Aperçu rapide pour PDGFRA anticorps (AA 698-727) (ABIN3032255)
Antigène
Voir toutes PDGFRA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 698-727
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Fonction
- PDGFR Antibody
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Réactivité croisée (Details)
- Expected species reactivity: Chicken, Mouse, Rat, Xenopus
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Purification
- Antigen affinity
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Immunogène
- A portion of amino acids 698-727 from the human alpha protein was used as the immunogen for this PDGFR antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the PDGFR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the PDGFR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
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Sujet
- As a receptor for PDGFA, PDGFR alpha promotes or inhibits cell proliferation and cell migration. Binding of its cognate ligands - homodimeric PDGFA, homodimeric PDGFB, heterodimers formed by PDGFA and PDGFB or homodimeric PDGFC -leads to the activation of several signaling cascades, the response depends on the nature of the bound ligand and is modulated by the formation of heterodimers between PDGFRA and PDGFRB. [UniProt]
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UniProt
- P16234
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Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
Antigène
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