PDK4 anticorps (AA 382-410)

N° du produit ABIN3028963

Cet anticorps Lapin Polyclonal détecte spécifiquement PDK4 dans WB, IHC, ELISA, IF et mIHC. Il présente une réactivité envers Humain et Souris et a été mentionné dans 1 publication.

Aperçu rapide pour PDK4 anticorps (AA 382-410) (ABIN3028963)

Antigène: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDK4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Multiplex Immunohistochemistry (mIHC)

Détail du produit anti-PDK4 anticorps

Épitope: AA 382-410

Purification: Purified

Immunogène: A portion of amino acids 382-410 from the human protein was used as the immunogen for this PDK4 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the PDK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:100,Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the PDK4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Références pour anticorps anti-PDK4 (ABIN3028963)

Sirait-Fischer, Olesch, Fink, Berkefeld, Huard, Schmid, Takeda, Brüne, Weigert: "Immune Checkpoint Blockade Improves Chemotherapy in the PyMT Mammary Carcinoma Mouse Model." dans: Frontiers in oncology, Vol. 10, pp. 1771, (2020) (PubMed).

Détails sur PDK4

Antigène: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Autre désignation: PDK4

Sujet: PDK4 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.

UniProt: Q16654

Pathways: Signalisation PI3K-Akt, Signalisation Hedgehog, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg