Bcl-2 anticorps (pThr56)
Aperçu rapide pour Bcl-2 anticorps (pThr56) (ABIN3030100)
Antigène
Voir toutes Bcl-2 (BCL2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- pThr56
-
Purification
- Antigen affinity purified
-
Immunogène
- This phospho-Bcl2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT56 of human Bcl-2.
-
Isotype
- Ig Fraction
-
-
-
-
Indications d'application
- Titration of the phospho-Bcl2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Aliquot the phospho-Bcl2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
-
Autre désignation
- Bcl-2
-
Sujet
- This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq].
-
UniProt
- P10415
-
Pathways
- Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
Antigène
-