SQSTM1 anticorps (pSer207)

N° du produit ABIN3031545

Cet anticorps anti-SQSTM1 Polyclonal Lapin (ABIN3031545) détecte spécifiquement SQSTM1 dans ELISA et DB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour SQSTM1 anticorps (pSer207) (ABIN3031545)

Antigène: SQSTM1 (Sequestosome 1 (SQSTM1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SQSTM1 est non-conjugé

Application: ELISA, Dot Blot (DB)

Détail du produit anti-SQSTM1 anticorps

Épitope: pSer207

Purification: Antigen affinity purified

Immunogène: This phospho-p62 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS207 of human p62/SQSTM1.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the phospho-p62 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the phospho-p62 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur SQSTM1

Antigène: SQSTM1 (Sequestosome 1 (SQSTM1))

Autre désignation: p62 SQSTM1

Sujet: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

UniProt: Q13501

Pathways: Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Autophagy