SPHK1 anticorps (AA 313-343)

N° du produit ABIN3032708

L’anticorps anti-SPHK1 Polyclonal Lapin est utilisé pour la détection de SPHK1 dans des échantillons de Humain. Il a été validé pour WB, ELISA, IHC et FACS.

Aperçu rapide pour SPHK1 anticorps (AA 313-343) (ABIN3032708)

Antigène: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPHK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Détail du produit anti-SPHK1 anticorps

Épitope: AA 313-343

Fonction: SPHK1 Antibody

Purification: Purified

Immunogène: A portion of amino acids 313-343 from the human protein was used as the immunogen for this SPHK1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the SPHK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the SPHK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur SPHK1

Antigène: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Autre désignation: SPHK1

Sujet: SPHK1 is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.

UniProt: Q9NYA1

Pathways: VEGF Signaling