Tuberin anticorps

N° du produit ABIN3029333

L’anticorps anti-Tuberin Monoclonal Souris est utilisé pour la détection de Tuberin dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA et IF.

Aperçu rapide pour Tuberin anticorps (ABIN3029333)

Antigène: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Tuberin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 249CT19-1-3

Détail du produit anti-Tuberin anticorps

Fonction: TSC2 Antibody

Purification: Purified

Immunogène: This TSC2 antibody was produced from a mouse immunized with TSC2 recombinant protein.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Titration of the TSC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles

Stock: -20 °C

Stockage commentaire: Aliquot the TSC2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Tuberin

Antigène: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Autre désignation: TSC2

Sujet: Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: P49815

Pathways: Signalisation RTK, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus