NDUFS1 anticorps (Internal Region)

N° du produit ABIN498087

Détail du produit anti-NDUFS1 anticorps

Antigène: NDUFS1 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1))

Épitope: Internal Region

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Lapin, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp NDUFS1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: C-TEKSATYVNT EGR

Réactivité croisée (Details): Species reactivity (expected):Rat, Canine (Dog), Bovine and RabbitSpecies reactivity (tested):Human, Mouse.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide from the internal region of the protein sequence according to NP_004997.4. Genename: NDUFS1

Information d'application

Indications d'application: Peptide ELISA: Detection Limit: 1/64000. Western blot: 0.3-1 μg/mL. Detects a band of Approx 80 kDa in Human Heart and Mouse Heart lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Species Reactivity: Tested: Human, Mouse. Expected from sequence similarity: Rat, Canine (Dog), Bovine and RabbitAdd. Information: Calculated Molecular Weight: 79.0 kDa according to NP_004997.4

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur NDUFS1

Antigène: NDUFS1 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1))

Autre désignation: NDUFS1 (NDUFS1 Produits)

Synonymes: anticorps 5830412M15Rik, anticorps 9930026A05Rik, anticorps CI-75Kd, anticorps CI-75k, anticorps PRO1304, anticorps NADH dehydrogenase (ubiquinone) Fe-S protein 1, anticorps NADH:ubiquinone oxidoreductase core subunit S1, anticorps Ndufs1, anticorps NDUFS1

Sujet: NDUFS1 belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. Ndufs1 has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in Ndufs1 gene are associated with complex I deficiency.Synonyms: CI-75kD, Complex I-75kD, NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

ID gène: 4719

NCBI Accession: NP_004997

UniProt: P28331