MAP2K4 anticorps

N° du produit ABIN498168

Détail du produit anti-MAP2K4 anticorps

Antigène: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP2K4 est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of MEK-4 protein. (region surrounding Gln253)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen

Pureté: > 95 % (by SDS-PAGE)

Information d'application

Indications d'application: Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur MAP2K4

Antigène: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Autre désignation: MAP2K4 (MAP2K4 Produits)

Synonymes: anticorps JNKK, anticorps JNKK1, anticorps MAPKK4, anticorps MEK4, anticorps MKK4, anticorps PRKMK4, anticorps SAPKK-1, anticorps SAPKK1, anticorps SEK1, anticorps SERK1, anticorps SKK1, anticorps Sek1, anticorps Serk1, anticorps MKK4A-l, anticorps map2k4, anticorps zgc:136500, anticorps jnkk, anticorps mek4, anticorps mkk4, anticorps sek1, anticorps jnkk1, anticorps serk1, anticorps xmek2, anticorps mapkk4, anticorps prkmk4, anticorps 142758_at, anticorps CG9738, anticorps CT27508, anticorps D-MKK4, anticorps DMKK4, anticorps Dmel\\CG9738, anticorps JNKK2, anticorps Mpk4, anticorps SEK1/MKK4, anticorps dMKK4, anticorps dMkk4, anticorps hep, anticorps ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4, anticorps ATMEK4, anticorps ATMKK4, anticorps F19C24.26, anticorps F19C24_26, anticorps MAP KINASE KINASE 4, anticorps mitogen-activated protein kinase kinase 4, anticorps MKK4B, anticorps zgc:194486, anticorps mitogen-activated protein kinase kinase 4, anticorps mitogen-activated protein kinase kinase 4a, anticorps MAP kinase kinase 4, anticorps mitogen activated protein kinase kinase 4, anticorps mitogen-activated protein kinase kinase 4b, anticorps MAP2K4, anticorps Map2k4, anticorps map2k4a, anticorps map2k4, anticorps Mkk4, anticorps MKK4, anticorps map2k4b

Sujet: The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK 5, whereas MEK-6 phosphorylates p38 and p38β. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.Synonyms: Dual specificity mitogen-activated protein kinase kinase 4, JNK-activating kinase 1, MAP Kinase Kinase 4, MAPKK4, MEK-4, MKK4, PRKMK4, SAPK/ERK kinase 1, SERK1, c-Jun N-terminal kinase kinase 1

Poids moléculaire: approx. 44 kDa

ID gène: 6416

NCBI Accession: NP_003001

UniProt: P45985

Pathways: Signalisation MAPK, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling