CSNK1A1 anticorps

N° du produit ABIN498265

Détail du produit anti-CSNK1A1 anticorps

Antigène: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CSNK1A1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of Casein Kinase I α protein.

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen

Pureté: > 95 % (by SDS-PAGE)

Information d'application

Indications d'application: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur CSNK1A1

Antigène: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Autre désignation: Casein Kinase I alpha (CSNK1A1 Produits)

Synonymes: anticorps CK1, anticorps CK1a, anticorps CKIa, anticorps HLCDGP1, anticorps PRO2975, anticorps 2610208K14Rik, anticorps 4632404G05Rik, anticorps 5430427P18Rik, anticorps Csnk1a, anticorps CHUNP6894, anticorps ck1alpha, anticorps wu:fb65a02, anticorps wu:fi30h04, anticorps wu:fj19c11, anticorps zgc:92158, anticorps KER1, anticorps ck1, anticorps CKIALPHA, anticorps CK-II, anticorps CSNK2A1, anticorps CG2028, anticorps CK I, anticorps CK1alpha, anticorps CKI, anticorps CKI alpha, anticorps CKIalpha, anticorps CkIa, anticorps Dmel\\CG2028, anticorps PKA-C, anticorps anon-WO03040301.93, anticorps anon-WO03040301.95, anticorps ck1a, anticorps dmCK1, anticorps dmckI, anticorps l(1)G0492, anticorps casein kinase 1 alpha 1, anticorps casein kinase 1, alpha 1, anticorps keratin 1, anticorps casein kinase 1 alpha 1 L homeolog, anticorps casein kinase 2 alpha 1, anticorps Casein kinase Ialpha, anticorps CSNK1A1, anticorps Csnk1a1, anticorps csnk1a1, anticorps KRT1, anticorps csnk1a1.L, anticorps CSNK2A1, anticorps CkIalpha

Sujet: Casein kinase I (also designated CKI) and casein kinase II (CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. Casein kinase I family members, which include casein kinase Iα, Iγ, Iδ and Iε, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an α2β2 or an αα'β2 structure. The a catalytic subunit is stimulated by the β regulatory subunit, which undergoes autophosphorylation. Casein kinase II activity is high in the cytosol and nucleus of proliferating and differentiating cells. Casein kinase II is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.Synonyms: CK1, CKI-alpha, CSNK1A1

Poids moléculaire: approx. 35 kDa

ID gène: 1452

NCBI Accession: NP_001883

UniProt: P48729

Pathways: Signalisation WNT, Signalisation Hedgehog