ELAVL2 anticorps

N° du produit ABIN498332

Détail du produit anti-ELAVL2 anticorps

Antigène: ELAVL2 (ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 2 (Hu Antigen B) (ELAVL2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ELAVL2 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects endogenous levels of Hel-N1 protein. (region surrounding Ser27)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen

Pureté: > 95 % (by SDS-PAGE)

Information d'application

Indications d'application: Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur ELAVL2

Antigène: ELAVL2 (ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 2 (Hu Antigen B) (ELAVL2))

Autre désignation: ELAVL2 / HUB (ELAVL2 Produits)

Synonymes: anticorps ELAVL2, anticorps HEL-N1, anticorps HELN1, anticorps HUB, anticorps Hub, anticorps mel-N1, anticorps Elav2, anticorps Xel-1, anticorps el-1, anticorps elavl2, anticorps elrB, anticorps hel-n1, anticorps heln1, anticorps hub, anticorps p45, anticorps zgc:91918, anticorps ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B), anticorps ELAV like RNA binding protein 2, anticorps ELAV like neuron-specific RNA binding protein 2 L homeolog, anticorps ELAV like neuron-specific RNA binding protein 2, anticorps ELAVL2, anticorps Elavl2, anticorps elavl2.L, anticorps elavl2

Sujet: The Elav-like genes encode for a family of RNA-binding proteins. Elav, a Drosophila protein and the first described member, is expressed immediately after neuroblastic differentiation into neurons and is necessary for neuronal differentiation and maintenance. Several mammalian Elav-like proteins, designated HuC, HuD and Hel-N1, are also expressed in postmitotic neurons. An additional mammalian homolog, HuR, which is also designated HuA, is ubiquitously expressed and is also overexpressed in a wide variety of tumors. Characteristically, these homologs all contain three RNA recognition motifs (RRM), and they specifically bind to AU-rich elements (ARE) in the 3'-untranslated region of mRNAs transcripts. ARE sites target mRNA for rapid degradation and thereby regulate the expression levels of genes involved in cell growth and differentiation.Synonyms: ELAV-like neuronal protein 1, ELAV-like protein 2, Hel-N1, Hu-antigen B, Nervous system-specific RNA-binding protein Hel-N1

Poids moléculaire: approx. 38 kDa

ID gène: 1993

NCBI Accession: NP_004423

UniProt: Q12926