14-3-3 gamma anticorps

N° du produit ABIN498437

Détail du produit anti-14-3-3 gamma anticorps

Antigène: 14-3-3 gamma (YWHAG1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp 14-3-3 gamma est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of 14-3-3 gamma protein. (region surrounding Met81)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate Buffered Saline (PBS), pH ~7.2, 15 mM Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur 14-3-3 gamma

Antigène: 14-3-3 gamma (YWHAG1)

Autre désignation: 14-3-3 Protein gamma (YWHAG1 Produits)

Synonymes: anticorps 14-3-3GAMMA, anticorps YWHAG, anticorps SRCRB4D, anticorps 14-3-3g, anticorps 14-3-3gamma, anticorps ywhag, anticorps 14-3-3G, anticorps D7Bwg1348e, anticorps cb47, anticorps fd20c02, anticorps wu:fd20c02, anticorps wu:fj53d01, anticorps zgc:73131, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma L homeolog, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide, anticorps 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1, anticorps YWHAG, anticorps ywhag.L, anticorps Ywhag, anticorps ywhag1

Sujet: 14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 beta, gamma, epsilon, zeta, eta, theta and sigma. 14-3-3 proteins form dimers that present two binding sites for ligand proteins, thereby bringing together two proteins that may not otherwise associate. These ligands largely share a 14-3-3 consensus binding motif and exhibit serine/threonine phosphorylation. 14-3-3 proteins function in broad regulation of these ligand proteins, by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzymatic activity and facilitation of protein modification, and thus loss of expression contributes to a vast array of pathogenic cellular activities.Synonyms: KCIP-1, Protein kinase C inhibitor protein 1, YWHAG

Poids moléculaire: approx. 28 kDa

ID gène: 7532

NCBI Accession: NP_036611

UniProt: P61981

Pathways: Myometrial Relaxation and Contraction, M Phase