TCEB3 anticorps

N° du produit ABIN498446

Détail du produit anti-TCEB3 anticorps

Antigène: TCEB3 (Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCEB3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of Elongin A1 protein. (region surrounding Arg129)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur TCEB3

Antigène: TCEB3 (Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3))

Autre désignation: TCEB3 (TCEB3 Produits)

Synonymes: anticorps CG6755, anticorps Dmel\\CG6755, anticorps Elo-A, anticorps dEloA, anticorps tceb3a, anticorps zgc:56638, anticorps wu:fw66g10, anticorps TCEB3, anticorps 110kDa, anticorps AA408125, anticorps Tceb3a, anticorps El, anticorps EloA, anticorps SIII, anticorps SIII p110, anticorps TCEB3A, anticorps Elongin A, anticorps transcription elongation factor B polypeptide 3, anticorps elongin A, anticorps calcium binding and coiled-coil domain 1b, anticorps elongin A S homeolog, anticorps transcription elongation factor B subunit 3, anticorps EloA, anticorps LOC413407, anticorps eloa, anticorps calcoco1b, anticorps ELOA, anticorps eloa.S, anticorps Eloa, anticorps TCEB3

Sujet: Individuals harboring germline mutations in the tumor suppressor gene von Hippel-Lindau (VHL) exhibit an increased susceptibility to a variety of tumors including renal carcinom,a hemangio-blastoma of the central nervous system and pheochromo-cytoma. The Elongin (SIII) complex has been identified as the functional target of the VHL protein. Elongin (SIII) is a heterotrimer composed of a transcriptional active subunit designated Elongin A and two regulatory subunits designated Elongin B and Elongin C. VHL functions by binding to the Elongin B and C subunits, inhibiting the transcriptional efficacy of the Elongin (SIII) complex. The VHL protein migrates with an apparent molecular weight of 38 kDa. The Elongin A subunit is 773 amino acids in length and has an apparent molecular weight of 110 kD,a while Elongin B and C are 18 kDa and 15 kDa proteins, respectively.Synonyms: EloA, Elongin 110 kDa subunit, Elongin A, Elongin-A, RNA polymerase II transcription factor SIII subunit A1, Transcription elongation factor B polypeptide 3

Poids moléculaire: approx. 78 kDa

ID gène: 6924

NCBI Accession: NP_003189

UniProt: Q14241