IFI16 anticorps

N° du produit ABIN499076

Détail du produit anti-IFI16 anticorps

Antigène: IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFI16 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects endogenous levels of IFI-16 protein. (region surrounding asn772)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen

Pureté: > 95 % (by SDS-PAGE)

Information d'application

Indications d'application: Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur IFI16

Antigène: IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))

Autre désignation: IFI16 / IFNGIP1 (IFI16 Produits)

Synonymes: anticorps IFNGIP1, anticorps PYHIN2, anticorps IFI16, anticorps Ifitm3l, anticorps Ifitml, anticorps interferon gamma inducible protein 16, anticorps interferon induced transmembrane protein 2, anticorps myeloid cell nuclear differentiation antigen-like protein, anticorps interferon-activable protein 203, anticorps IFI16, anticorps Ifitm2, anticorps LOC100156073, anticorps LOC488622, anticorps Ifi16

Sujet: Interferon-gamma inducible protein 16 (IFI16) belongs to the HIN-200 family of transcriptional regulator linked to cell cycle regulation and differentiation by modulating the activities of multiple transcriptional factors, such as p53 and Rb. The HIN-200 (hematopoeitic interferon-inducible nuclear antigens with 200 amino acid repeat) family members contain a DNA binding domain, a transcriptional regulatory domain, DAPIN/PAAD domain associated with interferon response and a binding domain for BRCA1. IFI16 may have a role in the regulation of hematopoeitic cell differentiation and also be involved in DNA repair since it becomes a component of the DNA repair multi-protein BASC complex after UV-induced DNA damage. IFI16 is strongly induced by gamma interferon in vivo.Synonyms: Gamma-interferon-inducible protein Ifi-16, IFI-16, Interferon-inducible myeloid differentiation transcriptional activator

Poids moléculaire: approx. 88 kDa

ID gène: 3428

NCBI Accession: NP_005522

UniProt: Q16666

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Autophagy, Inflammasome