NDUFS8 anticorps (Internal Region)

N° du produit ABIN499135

Détail du produit anti-NDUFS8 anticorps

Antigène: NDUFS8 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 8, 23kDa (NADH-Coenzyme Q Reductase) (NDUFS8))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp NDUFS8 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: C-EAEIAANIQA D

Specificité: Recognizes NDUFS8.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Canine.
Species reactivity (tested):Human, Rat.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_002487.1. Genename: NDUFS8

Information d'application

Indications d'application: Peptide ELISA: Limit Dilution: 1/4000. Western blot: 0.1-0.3 μg/mL. This antibody detects a band of approx. 25 kDa in Mouse and RatHeart lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur NDUFS8

Antigène: NDUFS8 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 8, 23kDa (NADH-Coenzyme Q Reductase) (NDUFS8))

Autre désignation: NDUFS8 (NDUFS8 Produits)

Synonymes: anticorps CI-23k, anticorps CI23KD, anticorps TYKY, anticorps BC021616, anticorps CI-23kD, anticorps ndufs8, anticorps wu:fb30b07, anticorps zgc:65835, anticorps zgc:77840, anticorps MGC85457, anticorps ND23, anticorps GB17476, anticorps DDBDRAFT_0169117, anticorps DDBDRAFT_0233205, anticorps DDB_0169117, anticorps DDB_0233205, anticorps zgc:109991, anticorps NADH:ubiquinone oxidoreductase core subunit S8, anticorps NADH dehydrogenase (ubiquinone) Fe-S protein 8, anticorps NADH dehydrogenase (ubiquinone) Fe-S protein 8a, anticorps NADH:ubiquinone oxidoreductase core subunit S8 L homeolog, anticorps NADH-quinone oxidoreductase subunit I, anticorps NADH dehydrogenase Fe-S protein 8, anticorps NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase), anticorps NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa, anticorps NADH dehydrogenase (ubiquinone) Fe-S protein 8b, anticorps NDUFS8, anticorps Ndufs8, anticorps ndufs8a, anticorps ndufs8.L, anticorps ndufs8, anticorps LOC551078, anticorps ndufs8b

Sujet: NDUFS8 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (may donate electrons to ubiquinone). Defects in NDUFS8 are a cause of Leigh syndrome (LS). LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions.Synonyms: CI-23kD, Complex I-23kD, NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, NADH-ubiquinone oxidoreductase 23 kDa subunit, TYKY subunit, mitochondrial

Poids moléculaire: 24.0kDa (Mouse NP_659119.2 and Rat NP_001099792.1).

ID gène: 4728

NCBI Accession: NP_002487

UniProt: O00217