BTK anticorps (N-Term)
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- Antigène Voir toutes BTK Anticorps
- BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
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Épitope
- N-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BTK est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Specificité
- BTK antibody was raised against a synthetic peptide corresponding to 16 amino acids near the amino-terminus of human BTK.
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- Human BTK / ATK / BPK (N-Terminus) Peptide
- Isotype
- IgG
- Top Product
- Discover our top product BTK Anticorps primaire
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- Indications d'application
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ELISA. Western Blot: BTK antibody can be used for the detection of BTK at 0.5 to 1 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- Antigène
- BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
- Autre désignation
- BTK (BTK Produits)
- Synonymes
- anticorps BTK, anticorps atk, anticorps bpk, anticorps xla, anticorps imd1, anticorps agmx1, anticorps psctk1, anticorps AGMX1, anticorps AT, anticorps ATK, anticorps BPK, anticorps IMD1, anticorps PSCTK1, anticorps XLA, anticorps AI528679, anticorps xid, anticorps Bruton tyrosine kinase, anticorps Bruton agammaglobulinemia tyrosine kinase, anticorps BTK, anticorps btk, anticorps Btk
- Sujet
- Bruton's tyrosine kinase (BTK) was initially identified as a member of the src family for protein-tyrosine kinases that was involved in X-linked aγ-globulinaemia (1), and has since been shown to involved in a number of signaling pathways in hemapoietic lineage (reviewed in 2). It has recently been shown to interact with members of the toll-like receptor (TLR) family such as TLR4, 6, 8, and 9 (3). The TLRs are critical molecules in both the innate and adaptive immunity and can recognize diverse microbial pathogens (reviewed in 4). BTK has also been shown to interact with key proteins involved in TLR4 signal transduction such as MyD88, TIRAP, and IRAK, but not TRAF-6, suggesting that BTK is involved in lipopolysaccharide signal transduction (3).Synonyms: AGMX1, ATK, Agammaglobulinaemia tyrosine kinase, B-cell progenitor kinase, BPK, Bruton tyrosine kinase, Tyrosine-protein kinase BTK
- ID gène
- 695
- UniProt
- Q06187
- Pathways
- Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling
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