CASP14 anticorps (C-Term)

N° du produit ABIN499557

Cet anticorps anti-CASP14 est un anticorps Lapin Polyclonal détectant CASP14 dans WB, IHC (p) et EIA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour CASP14 anticorps (C-Term) (ABIN499557)

Antigène: CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CASP14 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-CASP14 anticorps

Épitope: C-Term

Specificité: This antibody reacts to Caspase-14.

Purification: Affinity chromatography purified via peptide column

Immunogène: Caspase-14 antibody was raised against a 16 amino acid peptide from near the carboxy- terminus of human caspase-14.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: Caspase-14 antibody can be used for the detection of caspase-14 at 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur CASP14

Antigène: CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))

Autre désignation: Caspase-14

Sujet: Caspases are a family of cysteine proteases that can be divided into apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1b and IL-18. Caspase-14 is highly expressed in embryonic but not adult tissues. It is processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in the keratinocyte terminal differentiation, which is important for the formation of the skin barrier.Synonyms: CASP-14, CASP14

ID gène: 12365

NCBI Accession: NP_033939

UniProt: O89094