C1QTNF3
Reactivité: Humain
ELISA, WB
Hôte: Lapin
Polyclonal
HRP
Indications d'application
ELISA. Western Blot: CTRP3 antibody can be used for the detection of CTRP3 by Western blot at 1 -2 μg/mL. Mouse heart cell lysate can be used as positive control. These proteins are oftenhighly modified post-translationally and migrate in SDS-PAGE at positions other than theirpredicted size. Immunohistochemistry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Buffer
PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C.
Antigène
C1QTNF3
(C1q and Tumor Necrosis Factor Related Protein 3 (C1QTNF3))
anticorps Amacr, anticorps zgc:110704, anticorps C1ATNF3, anticorps CORCS, anticorps CORS, anticorps CORS-26, anticorps CORS26, anticorps CTRP3, anticorps 2310005P21Rik, anticorps Corcs, anticorps Cors, anticorps C1q and tumor necrosis factor related protein 3, anticorps alpha-methylacyl-CoA racemase, anticorps C1q and TNF related 3, anticorps C1QTNF3, anticorps amacr, anticorps C1qtnf3
Sujet
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). Multiple isoforms of human CTRP3 have been reported. It has been suggested that CTRP3 may play a role in skeletal development (5).Synonyms: C1ATNF3, CORS26, CTRP3, Complement C1q tumor necrosis factor-related protein 3, Secretory protein CORS26