Cyclic GMP anticorps (Alexa Fluor 750)

N° du produit ABIN4999947

Détail du produit anti-Cyclic GMP anticorps (Alexa Fluor 750)

Antigène: Cyclic GMP (cGMP)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclic GMP est conjugé à/à la Alexa Fluor 750

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Specificité: Due to the fact that BSA is used as the carrier, this antibody will cross-react with Albumin.

Réactivité croisée: Rat

Réactivité croisée (Details): cGMP

Purification: Purified by Protein A.

Immunogène: OVA conjugated cGMP

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Cyclic GMP

Antigène: Cyclic GMP (cGMP)

Autre désignation: cGMP (cGMP Produits)

Classe de substances: Chemical

Sujet:

Synonyms: Cyclic GMP, Cyclic guanosine monophosphate, Guanosine 3 5 Cyclic Monophosphate.

Background: Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).