COL25A1 anticorps (AA 581-654) (Alexa Fluor 750)

N° du produit ABIN5000127

Détail du produit anti-COL25A1 anticorps (Alexa Fluor 750)

Antigène: COL25A1 (Collagen, Type XXV, alpha 1 (COL25A1))

Épitope: AA 581-654

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COL25A1 est conjugé à/à la Alexa Fluor 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CLACP/COL25A1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur COL25A1

Antigène: COL25A1 (Collagen, Type XXV, alpha 1 (COL25A1))

Autre désignation: CLACP/COL25A1 (COL25A1 Produits)

Synonymes: anticorps COL25A1, anticorps AMY, anticorps CLAC, anticorps CLAC-P, anticorps CLACP, anticorps 2700062B08Rik, anticorps collagen type XXV alpha 1 chain, anticorps collagen, type XXV, alpha 1, anticorps COL25A1, anticorps col25a1, anticorps Col25a1

Sujet:

Synonyms: Alzheimer disease amyloid associated protein, AMY, CLAC, CLAC P, CLAC precursor, COL25A1, COL25A1 protein, Collagen alpha 1 XXV chain, Collagen alpha 1XXV chain, Collagen like Alzheimer amyloid plaque component, Collagen like Alzheimer amyloid plaque component precursor, Collagen type XXV alpha 1, Collagenous Alzheimer amyloid plaque component.

Background: Collagen proteins (products of the COL gene family) are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. The Collagen Type XXV precursor produces the proteolytic fragment CLAC (collagenous Alzheimer amyloid plaque component), which deposits in senile plaques associated with amyloid beta peptides (Abeta) in the brains of patients with Alzheimer's disease. CLAC binds to the fibrillized form of Abeta, which disturbs the structure and function of plasma membranes.