CTH anticorps (AbBy Fluor® 680)

N° du produit ABIN5000681

Cet anticorps anti-CTH est un anticorps Lapin Polyclonal détectant CTH dans WB et IF (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour CTH anticorps (AbBy Fluor® 680) (ABIN5000681)

Antigène: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTH est conjugé à/à la AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-CTH anticorps (AbBy Fluor® 680)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Cystathionine gamma lyase

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CTH

Antigène: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Autre désignation: CTH

Sujet:

Synonyms: CGL_HUMAN, CTH, Cystathionine gamma lyase, Cystathionine gamma-lyase, Cysteine desulfhydrase, Gamma cystathionase, Gamma-cystathionase, Homoserine deaminase, Homoserine dehydratase, MGC9471, CSE, Cystathionase.

Background: Catalyzes the last step in the transsulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure.Defects in CTH are the cause of cystathioninuria (CSTNU). It is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine, leading to increased urinary excretion.

ID gène: 1491

Pathways: ER-Nucleus Signaling, L'effet Warburg