FRMD8 anticorps (AA 65-170) (Alexa Fluor 750)

N° du produit ABIN5002918

Détail du produit anti-FRMD8 anticorps (Alexa Fluor 750)

Antigène: FRMD8 (FERM Domain Containing 8 (FRMD8))

Épitope: AA 65-170

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FRMD8 est conjugé à/à la Alexa Fluor 750

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FRMD8

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur FRMD8

Antigène: FRMD8 (FERM Domain Containing 8 (FRMD8))

Autre désignation: FRMD8 (FRMD8 Produits)

Synonymes: anticorps 1200004M23Rik, anticorps 2310035N23Rik, anticorps 4931429L16Rik, anticorps AU018809, anticorps RGD1310323, anticorps FERM domain containing 8, anticorps FERM domain containing 8 L homeolog, anticorps FRMD8, anticorps Frmd8, anticorps frmd8.L

Sujet:

Synonyms: FERM domain containing protein 8, FKSG44, FRMD8_HUMAN.

Background: FERM domains are roughly 150 amino acids in length and are found in a number of cytoskeletal-associated proteins such as Ezrin, Radixin, Moesin and 4.1 (erythrocyte membrane protein band 4.1), where they provide a link between cytoskeletal signals and membrane dynamics. FRMD8 (FERM domain-containing protein 8), also known as FKSG44, is a 464 amino acid protein containing one FERM domain. Existing as two alternatively spliced isoforms, the gene encoding FRMD8 maps to human chromosome 11q13.1. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4 % of human genomic DNA and is considered a gene and disease association dense chromosome. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

ID gène: 83786