MYBPC2 anticorps (C-Term)

N° du produit ABIN500298

Détail du produit anti-MYBPC2 anticorps

Antigène: MYBPC2 (Myosin Binding Protein C, Fast Type (MYBPC2))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYBPC2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human, mouse

Purification: Peptide affinity chromatography

Immunogène: MYBPC2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human MYBPC2.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Références pour anticorps anti-MYBPC2 (ABIN500298)

Emmanuele, Kubota, Garcia-Diaz, Garone, Akman, Sánchez-Gutiérrez, Escudero, Kariya, Homma, Tanji, Quinzii, Hirano: "Fhl1 W122S causes loss of protein function and late-onset mild myopathy." dans: Human molecular genetics, Vol. 24, Issue 3, pp. 714-26, (2015) (PubMed).

Détails sur MYBPC2

Antigène: MYBPC2 (Myosin Binding Protein C, Fast Type (MYBPC2))

Autre désignation: MYBPC2 (MYBPC2 Produits)

Synonymes: anticorps MYBPC, anticorps MYBPCF, anticorps im:7137115, anticorps im:7150089, anticorps zgc:110761, anticorps myosin binding protein C, fast-type, anticorps myosin binding protein C, fast type, anticorps myosin-binding protein C, fast-type, anticorps myosin binding protein C, fast type b, anticorps Mybpc2, anticorps MYBPC2, anticorps LOC520988, anticorps mybpc2b

Sujet: Myosin binding protein C (MYBPC) is a component of the thick filament of striated muscle, with the fast-type isoform designated MYBPC2. Both the fast-type and slow-type MYBPC protein contains seven immunoglobulin C2 motifs and three fibronectin type-III repeats. MYBPC2 is typically required for strong contractions and functions under anaerobic conditions. It is more similar to the cardiac isoform (MYBPC3) than to the slow-type isoform (MYBPC1) in terms of pCa50-indexed force development, length-independent cooperativity and length dependent activation. It has been suggested that in cardiac and fast muscle MYBPC2 contributes to an internal load, possibly by binding to actin via its N-terminal region.Synonyms: C-protein, Fast MyBP-C, MYBPCF, Myosin-binding protein C, skeletal muscle fast isoform

ID gène: 4606

NCBI Accession: NP_004524

UniProt: Q14324