Netrin 4 anticorps (AA 520-628) (Alexa Fluor 680)

N° du produit ABIN5007445

Détail du produit anti-Netrin 4 anticorps (Alexa Fluor 680)

Antigène: Netrin 4 (NTN4)

Épitope: AA 520-628

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Netrin 4 est conjugé à/à la Alexa Fluor 680

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Netrin 4

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Netrin 4

Antigène: Netrin 4 (NTN4)

Autre désignation: Netrin 4 (NTN4 Produits)

Synonymes: anticorps Netrin-4, anticorps PRO3091, anticorps RGD1565947, anticorps netrin 4, anticorps netrin-4, anticorps NTN4, anticorps ntn4, anticorps Ntn4, anticorps LOC100541214

Sujet:

Synonyms: Beta netrin, Beta-netrin, Hepar derived netrin like protein, Hepar-derived netrin-like protein, NET4_HUMAN, Netrin-4, Netrin4, NTN 4, NTN4.

Background: Netrin proteins are a family of laminin-related secreted proteins that provide guidance signals for axonal growth and cell migration during development. Netrin signaling is dependent on the concentration of calcium outside the cell and the level of PKA activity. In axonal cells, a reduction in PKA activity converts the responsiveness of the axons to the netrin proteins, as the cells are repelled, rather than attracted, by the netrin gradient. Netrin-4 is related to the Laminin chains, and is therefore also designated -netrin. It is present in the basement membranes of the vasculature, lateral olfactory tract, kidney and ovary. In humans, the gene encoding for the netrin-4 protein is localized to chromosome 12q22-q23. High levels of netrin-4 mRNA have also been detected in many cells and tissues, including cerebral cortex, hippocampus, amygdaloid nuclei and Purkinje cells. Netrin-4 is important in neural, kidney and vascular development.

ID gène: 59277