PCDHGB1 anticorps (AA 1-100) (Alexa Fluor 680)

N° du produit ABIN5008453

Détail du produit anti-PCDHGB1 anticorps (Alexa Fluor 680)

Antigène: PCDHGB1 (Protocadherin gamma Subfamily B, 1 (PCDHGB1))

Épitope: AA 1-100

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDHGB1 est conjugé à/à la Alexa Fluor 680

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PCDHGB1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PCDHGB1

Antigène: PCDHGB1 (Protocadherin gamma Subfamily B, 1 (PCDHGB1))

Autre désignation: PCDHGB1 (PCDHGB1 Produits)

Synonymes: anticorps PCDH-GAMMA-B1, anticorps protocadherin gamma subfamily B, 1, anticorps PCDHGB1, anticorps Pcdhgb1

Sujet:

Synonyms: PCDH gamma B1, Protocadherin gamma B1, Protocadherin gamma B1 precursor, Protocadherin gamma subfamily B 1, MGC119466, MGC119467, MGC119469, PCDGD_HUMAN.

Background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. The protocadherein gamma cluster consists of three subfamilies (A, B and C). As a member of the gamma subfamily B, PCDHGB1 (Protocadherin gamma B1) is a 927 amino acid protein that is one of 22 proteins encoded by the protocadherin gamma cluster. Typical of gamma protocadherins, PCDHGB1 contains six cadherin motifs and is a type I transmembrane receptor expressed in the central nervous system. With localization to synapses, members of the gamma cluster of protocadherins are essential for neuronal survival. There are two isoforms of PCDHGB1 that are produced as a result of alternative splicing events.