TBC1D1 anticorps (C-Term)

N° du produit ABIN500871

Détail du produit anti-TBC1D1 anticorps

Antigène: TBC1D1 (TBC1 (Tre-2/USP6, BUB2, Cdc16) Domain Family, Member 1 (TBC1D1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TBC1D1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects TBC1D1 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Peptide afiinity chromatography

Immunogène: TBC1D1 antibody was raised against a 22 amino acid peptide from near the carboxy terminus of human TBC1D1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur TBC1D1

Antigène: TBC1D1 (TBC1 (Tre-2/USP6, BUB2, Cdc16) Domain Family, Member 1 (TBC1D1))

Autre désignation: TBC1D1 (TBC1D1 Produits)

Synonymes: anticorps TBC1D1, anticorps TBC, anticorps TBC1, anticorps 1110062G02Rik, anticorps AI385682, anticorps AW555803, anticorps Tbc1, anticorps mKIAA1108, anticorps TBC1 domain family member 1, anticorps TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1, anticorps TBC1 domain family, member 1, anticorps TBC1D1, anticorps tbc1d1, anticorps LOC100523386, anticorps Tbc1d1

Sujet: TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain and presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2/USP6, yeast Bub2, and CDC16. TBC1D1 and TBC1D4 (AS160) have been demonstrated to be Rab GAPs (GTPase-activating proteins) that link upstream to Akt and phosphoinositide 3-kinase and downstream to Rabs involved in trafficking of GLUT4 vesicles. TBC1D1 regulates insulin-mediated GLUT4 translocation through its GAP activity, and is a likely Akt substrate. Mutations in the Tbc1d1 gene lead to some cases of severe human obesity.Synonyms: KIAA1108, TBC1 domain family member 1

ID gène: 23216

NCBI Accession: NP_055988