PRKAA2 anticorps
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- Antigène Voir toutes PRKAA2 Anticorps
- PRKAA2 (Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp PRKAA2 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Réactivité croisée
- Humain
- Purification
- Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Immunogène
- This PRKAA2 monoclonal antibody is generated from mouse immunized with PRKAA2 recombinant protein.
- Clone
- 6C2
- Isotype
- IgG2a
- Top Product
- Discover our top product PRKAA2 Anticorps primaire
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- Indications d'application
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WB 1:300-5000
IF() - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C for 12 months.
- Date de péremption
- 12 months
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- Antigène
- PRKAA2 (Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))
- Autre désignation
- PRKAA2 (PRKAA2 Produits)
- Synonymes
- anticorps AMPK, anticorps AMPK2, anticorps AMPKa2, anticorps PRKAA, anticorps Ampk, anticorps Ampka2, anticorps 2310008I11Rik, anticorps A830082D05, anticorps AMPKalpha2, anticorps AMPKA2, anticorps ampk, anticorps ampk2, anticorps prkaa, anticorps prkaa1, anticorps PRKAA2, anticorps protein kinase AMP-activated catalytic subunit alpha 2, anticorps protein kinase, AMP-activated, alpha 2 catalytic subunit, anticorps protein kinase, AMP-activated, alpha 2 catalytic subunit S homeolog, anticorps PRKAA2, anticorps Prkaa2, anticorps prkaa2.S, anticorps prkaa2
- Sujet
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Synonyms: AMPK, AMPK2, PRKAA, AMPKa2, 5'-AMP-activated protein kinase catalytic subunit alpha-2, AMPK subunit alpha-2, Acetyl-CoA carboxylase kinase, ACACA kinase, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, PRKAA2
Background: The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
- ID gène
- 5563
- UniProt
- P54646
- Pathways
- AMPK Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, L'effet Warburg
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