SEMA3E anticorps (AA 401-450) (Alexa Fluor 750)

N° du produit ABIN5010348

Détail du produit anti-SEMA3E anticorps (Alexa Fluor 750)

Antigène: SEMA3E (Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3E (SEMA3E))

Épitope: AA 401-450

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SEMA3E est conjugé à/à la Alexa Fluor 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris

Homologie: Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SEMA3E/Semaphorin 3E

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SEMA3E

Antigène: SEMA3E (Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3E (SEMA3E))

Autre désignation: SEMA3E/Semaphorin 3E (SEMA3E Produits)

Synonymes: anticorps M-SEMAH, anticorps M-SemaK, anticorps SEMAH, anticorps coll-5, anticorps 6430702L12, anticorps AA408817, anticorps Semah, anticorps mKIAA0331, anticorps semaphorin 3E, anticorps sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E, anticorps SEMA3E, anticorps Sema3e

Sujet:

Synonyms: Coll 5, Coll5, KIAA0331, M sema H, M SEMAH, M SemaK, Msema H, MSEMAH, MSemaK, SEM3E_HUMAN, Sema domain immunoglobulin domain Ig, Sema domain immunoglobulin domain Ig short basic domain secreted 3E, Sema domain, immunoglobulin domain Ig, short basic domain, secreted, semaphorin 3E, SEMA3E, SEMAH, Semaphorin 3E, Semaphorin-3E, Semaphorin3E, Short basic domain secreted semaphorin 3E, SEM3E_HUMAN.

Background: Semaphorins are a family of cell surface and secreted proteins involved in neural development that are conserved from insects to humans. Members of this family are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular semaphorin? domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. The transmembrane semaphorins are characterized by an additional 80 amino acid transmembrane domain and an 80-110 amino acid cytoplasmic domain. Secreted and cell-bound semaphorins chemically attract and repel the growth of neural axons, guiding the development of intricate networks of neural tissue. SEMA3E is a secreted semaphorin with 775 amino acids. Mutations in the SEMA3E gene are associated with CHARGE syndrome, a disorder characterized by cranial nerve dysfunction, coloboma of the eye, choanal atresia, inner and external ear abnormalities, cardiac anomalies, genitourinary abnormalities, and growth retardation.